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Pharmaceutical Nitroglycerin


Biomedical, incl. Biotech

Pharmaceutical Nitroglycerin


The project resulted in licensed and commercialized products – metered dose sprays for sublingual application of glycerol trinitrate (GTN).

The patch for transdermal delivery of GTN - the product is developed and tested on the laboratory level.

The project includes:
1: production of highly pure nitroglycerin (NG) in suitable premixes,
2: production of metered-dose pocket spray for buccal administration of NG in prevention of
acute attacks of Angina pectoris, Asthma cardiale, lung edema, renal and biliary colic,
spastic migraine and other pathologic conditions where is necessary a rapid relaxation of
smooth muscles,
3: production of patches for transdermal delivery of NG in long-term prevention of above
indicated vasospastic conditions.

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